目的构建肾移植患者饮食管理知识图谱，为下一步临床智能应用提供基础和保障。方法以成人肾移植患者饮食管理的证据总结为基础，通过《肾小幺的移植日常：肾移植健康管理》《肾移植患者自我管理指南》《肾移植手册》《肾病营养治疗手册》等书籍、中国知网、万方、中国生物医学数据库、Pubmed、Web of Science、Embase等数据库以及医脉通、MedSci等健康网站进行资料扩充，采用本体构建7步法和Protégé工具，自顶向下进行知识图谱构建，并将“实体-关系-实体”三元组数据输入Neo4j图数据库进行存储。结果本研究以管理团队、管理细则、知识指导等为一级知识框架共构建出812种知识实体及6种实体间的关系。 结论构建的知识图谱系统展示了肾移植患者饮食管理的相关知识，为其智能化发展奠定了重要基础。研究仅限于知识图谱构建，其临床价值仍需通过后续开发应用系统进行验证。

Objective To construct a knowledge graph for dietary management of kidney transplant recipients，so as to provide a foundation and guarantee for future clinical intelligent applications.MethodsBased on “Evidence Summary for Dietary Management in Adult Kidney Transplant Recipients”，information was expanded using resources including the books “Daily Life After Transplantation with Xiao Yao the Kidney Recipient:Health Management for Kidney Transplantation”，“Self-Management Guide for Kidney Transplant Recipients”，“Kidney Transplantation Manual”，“Nutritional Therapy Manual for Kidney Disease”，and databases such as CNKI，Wanfang，CBM，PubMed，Web of Science，Embase，as well as health websites like Medlive and MedSci.The knowledge graph was constructed in a top-down manner using the 7-step ontology construction method and the Protégé tool.The “Entity-Relation-Entity” triplet data was imported into the Neo4j graph database for storage.Results The study established a primary knowledge framework including management team，detailed management rules，and knowledge guidance，ultimately constructing 812 knowledge entities and 6 types of inter-entity relationships.Conclusions The constructed knowledge graph systematically displays relevant knowledge for the dietary management of kidney transplant recipients，laying an important foundation for its intelligent development.This study is limited to the construction of the knowledge graph;its clinical value still requires validation through subsequent development and application systems.

R473.6

2025年度杭州市卫生健康科技计划（B20252779）