目的 总结乙型肝炎病毒（hepatitis B virus，HBV）感染产妇母乳喂养管理的最佳证据，为临床实践提供循证依据。 方法 依据“6S”证据模型，系统检索国内外指南网、数据库及相关专业协会网站中关于HBV感染产妇母乳喂养的证据，检索时限为建库至2025年6月。由多名研究人员独立进行质量评价、证据提取与汇总。 结果 共纳入15篇文献，包括系统评价1篇、证据总结2篇、指南7篇、专家共识3篇、随机对照试验1篇、队列研究1篇，围绕评估与治疗、健康宣教、产后随访、再次妊娠4个方面汇总了21条证据。 结论 HBV感染产妇母乳喂养管理的最佳证据可为临床实践提供参考，建议医护人员早期全面筛查、加强宣教、消除产妇顾虑并追踪随访，确保母婴安全。

Objective To summarize the best evidence of breastfeeding management among parturients with hepatitis B virus (HBV) infection,and to provide evidence-based basis for clinical practice.Methods According to the 6S evidence model,a systematic search was conducted for domestic and foreign guidelines,databases and related professional association websites on breastfeeding among parturients with HBV infection.The retrieval period was from the inception to June 2025.Quality assessment,data extraction and evidence collection were conducted independently by multiple researchers. Results A total of 15 studies was included,with 1 systematic review,2 evidence summaries,7 guidelines,3 expert consensuses,1 randomized controlled trial and 1 cohort study.A total of 21 pieces of evidence were summarized across 4 domains:assessment and treatment,health education,postpartum follow-up,and subsequent pregnancy.Conclusions The best evidence of breastfeeding management among parturients with HBV infection could provide evidence-based basis for clinical practice. It is recommended that medical staff conduct comprehensive early screening, enhance education and publicity, eliminate the concerns of parturients and carry out follow-up visits to ensure the safety of mothers and infants.

R473.71

山东省本科高校教学改革研究项目（XM2023072）