目的 汇总国内外精神障碍肌少症患者运动干预相关证据，为临床开展循证实践提供参考。方法 按照“6S”证据模型检索，系统检索国内外网站和数据库中有关精神障碍肌少症患者运动干预的相关证据，检索时限为各数据库建库至2023年10月，由2名研究者独立进行文献质量评价、证据提取和汇总。结果 共纳入16篇文献，包括指南4篇、专家共识1篇、临床决策2篇、系统评价9篇，从组织管理、运动获益、运动场所、运动对象、运动评估、运动方案、依从性管理、效果评价8个方面总结31条证据。结论 汇总的精神障碍肌少症患者运动干预证据具有科学性和实用性，可以为临床实践提供参考。

Objective To integrate relevant evidence on exercise intervention in mental disorder patients with sarcopenia and to provide references for clinical practice.Methods Following the 6S evidence model,the evidence of exercise intervention in mental disorder patients with sarcopenia from domestic and foreign databases was systematically searched from the inception of databases until October 2023.Two researchers independently performed literature quality assessment,evidence extraction,and synthesis.Results A total of 16 articles were involved,with 4 guidelines,1 expert consensuse,2 clinical decisions and 9 systematic reviews.Thirty-one evidence items were summarized across eight domains：organizational management,exercise benefits,exercise settings,target population,assessment methods,exercise protocols,adherence management,and outcome evaluation.Conclusions The best evidence for exercise intervention in mental disorder patients with sarcopenia is scientific and clinically practical,offering valuable guidance for evidence-based practice.

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上海交通大学医学院护理学科建设项目（SJTUHLXK2023）；上海交通大学护理学院“护理+X”交叉研究基金项目（HLXKGDD2024）；复旦大学循证护理中心第7期“证据转化与临床应用工作坊”（Fudanebn202207）；老年长期照护教育部重点实验室开放基金项目（LNYB-2023-06）