目的 了解晚期肺癌患者生存痛苦现状及其影响因素，为降低肺癌患者的生存痛苦水平提供依据。方法 2024年2-12月，采用便利抽样法选取湖南省2所三级甲等医院肿瘤科收治的333例晚期肺癌患者为调查对象。采用一般资料调查表、生存痛苦量表(existential distress scale,EDS) 、简易疾病感知问卷 (brief illness perception questionnaire,B-IPQ)、安德森症状评估量表肺癌模块(lung cancer module of M.D.Anderson symptom inventory,MDASI-LC)、自我同情量表(self-compassion scale,SCS)和数字评分量表对其进行调查。结果 晚期肺癌患者生存痛苦总分为6.00（2.00,14.00）分。多重线性回归分析结果显示，自我同情、疼痛程度和疾病感知是影响晚期肺癌患者生存痛苦的重要因素（均P＜0.05）。结论 晚期肺癌患者的生存痛苦处于较低水平，其中价值感缺失较强烈。医护人员应尽早识别晚期肺癌患者的生存痛苦水平，并针对影响因素，采取个性化的干预措施。

Objective To investigate the current status and influencing factors of existential distress in patients with advanced lung cancer,and to provide evidence for reducing the level of their existential distress.Methods From February to December 2024,333 patients with advanced lung cancer from two tertiary A hospitals in Hunan Province were conveniently sampled and surveyed using General Information Questionnaire,Existential Distress Scale (EDS),Brief Illness Perception Questionnaire (B-IPQ),Lung Cancer Module Of M.D.Anderson Symptom Inventory (MDASI-LC),Self-Compassion Scale (SCS),and Numerical Rating Scale.Results The total existential distress score of advanced lung cancer patients was 6.00(2.00,14.00).The multiple linear regression analysis showed that self-compassion,pain level,and illness perception were significant influential factors of existential distress in advanced lung cancer (all P＜0.05).Conclusions Patients with advanced lung cancer experience relatively low levels of existential distress overall,but report strong feelings of worthlessness.Healthcare providers should early identify existential distress levels and implement personalized interventions targeting influencing factors to alleviate patients’ suffering.

R473.73

湖南省卫生健康委科研计划项目（202214013919）