目的 探讨辅助生殖技术（assisted reproductive technology,ART）助孕女性经济毒性的现状及其影响因素，为制订针对性干预措施提供依据。方法 2024年9-12月，采用便利抽样法选取湖南、广西两省3所三级甲等医院生殖中心就诊的314例ART助孕女性为研究对象，采用患者报告结局经济毒性综合评分量表（comprehensive scores for financial toxicity based on the patient-reported outcome measure，COST-PROM）、中文版不孕症生育压力简式量表（Chinese version of the COMPI fertility problem stress scale，COMPI-FPSS）、感知伴侣回应性量表（perceived partner responsiveness scale，PPRS）、心理弹性量表（Connor-Davidson resilience scale，CD-RISC） 对其进行调查。结果 ART助孕女性COST-PROM得分为（15.72±7.55）分，其中92.04%（289例）存在经济毒性。多元线性回归分析显示，门诊报销比例、家庭储蓄、助孕次数、异地医疗、ART相关并发症、生育压力、心理弹性是经济毒性的影响因素（均P＜0.01），解释总变异的41.74%。结论 ART助孕女性普遍存在经济毒性，医护人员应早期识别高危人群，并根据影响因素制订针对性生育护理策略，以降低该人群的经济毒性水平。

Objective To explore the current status and influencing factors of financial toxicity among female patients undergoing assisted reproductive technology (ART),and to provide a basis for formulating targeted intervention strategies.Methods Convenience sampling method was employed to select 314 female patients undergoing ART treatment in three tertiary A hospitals located in Hunan and Guangxi provinces from September to December 2024.Comprehensive Scores for Financial Toxicity Based on the Patient-Reported Outcome Measure（COST-PROM）,Chinese Version of the COMPI Fertility Problem Stress Scale（COMPI-FPSS）,Perceived Partner Responsiveness Scale（PPRS）,and Connor Davidson Resilience Scale（CD-RISC）were used for investigation.Results The COST-PROM score was 15.72±7.55,with 92.04% (n=289) experiencing financial toxicity.The multiple linear regression analysis showed that outpatient reimbursement ratio,family savings,number of assisted pregnancies,remote medical treatment,ART-related complications,fertility pressure and psychological resilience were the main influencing factors of financial toxicity (all P＜0.01),explaining 41.74% of the total variation.Conclusions Financial toxicity is prevalent among ART-treated women.Healthcare providers should identify high-risk groups early and formulate tailored reproductive care strategies according to influencing factors to reduce the level of financial toxicity.

R473.71

湖南省哲学社会科学基金项目（22YBX024）