目的 评价亲水涂层导尿管在留置导尿患者中的应用效果。方法 检索PubMed、Web of Science、Wiley、EBSCO、Cochrane Library、Ovid、ProQuest、中国生物医学文献数据库、中国知网、维普和万方数据库，检索使用亲水涂层导尿管和普通导尿管行留置导尿的随机对照试验文献。以RevMan 5.4、Stata 18.0软件进行统计分析。 结果 共纳入文献10篇，共计5660例患者。亲水涂层导尿管组和普通导尿管组在菌尿阳性率、血尿发生率、漏尿发生率中差异均无统计学意义（均P＞0.05）；但ICU患者中，亲水涂层导尿管组在抗菌效果方面优于对照组（P＜0.05）。结论 亲水涂层导尿管在留置导尿管患者中的整体优势并不显著，但在ICU患者中可能具有潜在的抗菌效果。

Objective To evaluate the effects of hydrophilic coated catheters in patients with indwelling catheterization.Methods Literature of randomized controlled trials comparing hydrophilic coated catheters with ordinary catheters for indwelling catheterization was retrieved from databases including PubMed,Web of Science,Wiley,EBSCO,Cochrane Library,Ovid,ProQuest,CBM,CNKI,VIP,and WanFang.Statistical analysis was conducted using RevMan 5.4 and Stata software 18.0.Results A total of 10 articles involving 5660 patients were included.The results showed no statistical significance between the two groups in the positive rate of bacteriuria,the incidence of hematuria,and the incidence of leakage(P＞0.05).However,in ICU patients,the coated group demonstrated superior antibacterial effects compared to the control group (P＜0.05).Conclusions Hydrophilic-coated catheters do not show significant overall advantages in patients with indwelling catheters,but they may have potential antibacterial benefits in ICU patients.

R473.51

中国博士后科学基金第74批面上资助（2023M742483）