目的 探讨湿润烧伤膏应用于麻风病并发足部溃疡患者的临床疗效,为提高其治疗效果提供新方法.方法 2022年 1月至2023年12月,采用便利抽样选取某院麻风病区麻风病并发足溃疡患者80例为研究对象,采用随机数字表法将其分为观察组和对照组,每组40例.两组患者均给予常规诊疗措施,对照组创面给予常规红霉素软膏治疗,而观察组给予湿润烧伤膏治疗,持续30d.评估两组患者溃疡的治疗效果、新发病率和复发率、自我护理能力、患者满意度和费用等.结果 观察组治疗有效率为92．50%,明显高于对照组的50．00%,差异有统计学意义(P＜0．001);且观察组新发溃疡及2个月后溃疡复发率均低于对照组,差异均有统计学意义(均P＜0．001);观察组自护能力及满意度均亦高于对照组,而治疗费用低于对照组,差异均有统计学意义(均P＜0．001).结论 湿润烧伤膏在麻风病并发足部溃疡患者中应用效果显著,且费用低,患者满意度较高,值得推广.

Objective To explore the clinical effect of Moisture Exposed Burn Ointment(MEBO) in patients with leprosy-associated foot ulcers,and to provide a new method to improve the therapeutic effect of patients with related ulcers.Methods From January,2022 to December 2023,80 patients with leprosy-associated foot ulcers from the leprosy ward of a hospital were selected by the convenience sampling method.The patients were randomly divided into the observation group and the control group by the random number table method,with 40 cases in each group.Both groups were given conventional diagnosis and treatment measures.The control group was treated with conventional erythromycin ointment on the wound surface,while the observation group was treated with MEBO.The treatment lasted for 30 days.The therapeutic effect of ulcers,new incidence rate and recurrence rate,self-care ability,patient satisfaction and cost were evaluated in both groups.Results The effective rate in the observation group was 92.50%,which was significantly higher than that in the control group(50.00%),the difference was statistically significant(P＜0.001).The rates of new ulcer and ulcer recurrence after 2 months in the observation group were lower than those in the control group,with statistical significance(all P＜0.001).The self-care ability and satisfaction of the observation group were higher than those of the control group,while the treatment cost was lower,with statistical significance(all P＜0.001).Conclusions MEBO is effective in patients with leprosy-associated foot ulcer,with low cost and high patient satisfaction.It is worth promoting.

R475．51;R248

海南省自然科学基金高层次人才项目(821RC566)；海南省哲学社会科学规划课(RZ2300005753)