目的 通过系统评价再评价，综合评估认知刺激（cognitive stimulation，CS）干预失智症患者有效性的证据，为照护者提供依据。方法 检索Cochrane Library、Joanna Briggs Institute、PsycInfo、PubMed、Web of Science、Embase、CINAHL、中国知网、万方、维普以及中国生物医学文献数据库，收集CS干预失智症患者的系统评价。检索时间均为建库至2024年8月26日。采用AMSTAR 2(assessment of multiple systematic reviews 2)和GRADE(grades of recommendations assessment development and evaluation)系统分别进行方法学质量评价和证据质量评价。结果 共纳入9篇系统评价。方法学质量评价结果显示，2篇为高级质量、1篇为中级质量、3篇为低级质量、3篇为极低级质量。证据质量评价的结果显示，6个结局指标33条证据体中，3条为高质量、14条为中质量、10条为低质量、6条为极低质量。结论 CS能改善失智症患者的认知功能、生活质量和社会互动，但对神经精神症状、情绪以及日常生活活动能力的干预效果仍需进一步验证。

Objective To comprehensively evaluate the evidence on the effectiveness of cognitive stimulation(CS) in the intervention of patients with dementia through an overview of systematic reviews,so as to provide evidence for caregivers.Methods To collect systematic reviews of CS interventions in patients with dementia,Cochrane Library,Joanna Briggs Institute,PsycInfo,PubMed,Web of Science,Embase,CINAHL,CNKI,Wanfang,VIP and CBM were searched.The retrieval period was from the inceptions to August 26, 2024.Assessment of multiple systematic reviews 2(AMSTAR 2) was used for methodological quality evaluation and grades of recommendations assessment development and assessment(GRADE) system for evidence quality evaluation.Results A total of 9 systematic reviews were included.The results of methodological quality evaluation showed that 2 reviews were of high quality,1 of intermediate quality,3 of low quality and 3 of very low quality.The results of evidence quality evaluation showed that among 33 evidence bodies of 6 outcome indicators,3 of high quality,14 of medium quality,10 of low quality,and 6 of very low quality.Conclusions CS can improve cognitive function,quality of life and social interaction in patients with dementia,but the effect of intervention on neuropsychiatric symptoms,mood and activity of daily living(ADL) needs to be further verified.

R473.74

贵州省卫生健康委科学技术基金项目(gzwkj2024-548)；贵州省中医药管理局项目 (QZYY-2021-164)；贵州省高校人文社会科学研究项目（24RWZX061）