目的 整合连续性肾脏替代治疗预防非计划下机过程管理的最佳证据，为医护人员提供规范、科学的预防及管理循证依据。方法 根据证据资源“6S”模型，系统检索临床决策系统、指南及专业医学会网站、循证数据库及综合数据库中有关连续性肾脏替代治疗预防非计划下机过程管理的相关文献，检索时限为2017年8月15日至2023年8月15日。由4名研究者筛选文献并进行质量评价，提取并汇总证据。结果 共纳入18篇文献,其中指南2篇、临床决策5篇、JBI推荐实践1篇、共识4篇、证据总结3篇、系统评价3篇。从组织管理、上机前管理、运行管理及停机后管理4个方面汇总，共形成30条证据。结论 总结的最佳证据具有科学性和实用性，对预防非计划下机过程管理有指导意义。

Objective To summarize the best evidence on process management of unscheduled termination for continuous renal replacement therapy (CRRT),and to provide medical staff with standardized and scientific evidence-based basis for prevention and management.Methods According to the “6S” model of evidence resources,literatures were systematically searched in clinical decision systems,guidelines and professional medical association websites,evidence-based databases and comprehensive databases from August 2017 to August 15,2023. Four researchers screened the literatures,evaluated the quality,extracted and summarized the evidence. Results A total of 18 articles were included,with 2 guidelines,5 clinical decisions,1 JBI recommended practice,4 consensuses,3 evidence summaries and 3 systematic reviews. A total of 30 pieces of evidence were summarized from 4 aspects,namely administration management,pre-operation management,operation management and post-operation management. Conclusion The best evidence summarized is scientific and practical,and of significance for the process management of unscheduled termination.

R47-05；R473

河北省医学科学研究课题（20210797）