目的 系统评价经皮冠状动脉介入（percutaneous coronary intervention，PCI）术后患者药物依从性的障碍和促进因素，为制订药物依从性干预策略提供依据。方法 采用混合研究系统评价设计，系统检索PubMed、Embase、CINAHL、Web of Science、中国知网、万方、CBM 等中英文数据库，筛选PCI术后患者药物依从性相关研究,检索时限为建库至2023年3月1日。以能力、机会、动机和行为（capability,opportunity,motivation,behavior，COM-B）模型的6个子组件为基础，对PCI术后患者药物依从性的障碍和促进因素进行分析。结果 共纳入15篇研究，包括3篇质性研究、5篇横断面和7篇队列研究；确定30个影响因素，归纳为身体能力、心理能力、反射性动机、自发性动机、物理机会、社会机会等6个类别。结论 建议根据PCI术后患者COM-B模型 6 个类别确定的药物依从性障碍和促进因素，采取多方面策略，解决多个领域的因素，以促进PCI术后患者药物依从性的提升。

Objective To systematically review the barriers and promoting factors of medication adherence in patients after percutaneous coronary intervention (PCI),and to provide reference for formulating intervention strategies for medication adherence. Methods PubMed,Embase,CINAHL,Web of Science,CNKI,Wanfang,CBM and other Chinese and English databases were systematically searched to screen studies on medication adherence in patients after PCI from the inception to March 1,2023. Based on the 6 subcomponents of ability,opportunity,motivation and behavior (COM-B) model,barriers and promoting factors of postoperative PCI patients were analyzed in terms of medication adherence. Results A total of 15 studies were included,with 3 qualitative studies,5 cross-sectional studies and 7 cohort studies. Thirty influencing factors in 6 categories were identified,namely physical capability,psychological capability,reflective motivation,automatic motivation,physical opportunity and social opportunity. Conclusion According to the 6 categories of COM-B model for patients after PCI,it is recommended to adopt multiple strategies to solve the factors in multiple fields,so as to improve the medication adherence of patients after PCI.

R47-05;R473.54