目的 了解膀胱灌注化疗患者经济毒性现况并分析原因，为制订干预措施提供参考依据。方法 便利抽样法选取太原市3所三级甲等医院泌尿外科418例行膀胱癌术后灌注化疗患者为调查对象，采用一般资料调查表、癌症患者报告结局的经济毒性评分量表、心理弹性量表、领悟社会支持量表对其进行调查并分析经济毒性的影响因素。结果 膀胱灌注化疗患者经济毒性得分为20.00（18.5，23.5）分；多元线性回归分析显示，患者年龄、家庭收入、受教育程度、医保类型、心理弹性和社会支持度是主要影响因素（均P＜0.01）。结论 膀胱灌注化疗患者普遍存在经济毒性，且影响因素较多，医护人员应早期识别其经济毒性、制订个体化干预措施、运用“优势视角”理论增强患者应对疾病的信心，提升其心理弹性水平并充分利用社会支持资源以降低患者的经济毒性水平。

Objective To understand the financial toxicity of postoperative intravesical chemotherapy in patients with bladder cancer and analyze the reasons,so as to provide a basis for formulating intervention measures.Methods A total of 418 patients with bladder perfusion chemotherapy in the Department of Urology of 3 tertiary A hospitals in Taiyuan,Shanxi Province were the objects of convenience sampling.The general information questionnaire,the comprehensive score for financial toxicity for cancer patients,the psychological resilience scale,and the perceived social support scale were used for the investigation.Multivariate linear regression analysis was used to analyze the influencing factors of financial toxicity.Results The financial toxicity score of patients with bladder perfusion chemotherapy was 20.00 (18.5,23.5).Multiple linear regression analysis showed that age,family income,education level,medical insurance type,psychological resilience and social support were the main influencing factors (all P＜0.01).Conclusions Patients with intravesical chemotherapy generally have financial toxicity,and there are many factors affecting it.Medical staff should not only identify it early and formulate individualized measures of intervention,but also use the theory of “advantage perspective” to enhance patients’ confidence in dealing with the disease,improve psychological resilience and make full use of social support resources to reduce the financial toxicity of their patients.

R473.73