目的 分析自悯在白血病患儿父母疾病进展恐惧（fear of progression，FoP）与创伤后应激障碍（post-traumatic stress disorder，PTSD）症状间的中介作用，为其心理健康管理提供依据。方法 便利抽样法选取广州市3所三级甲等医院门诊及住院治疗的219名白血病患儿父母为研究对象，采用父母疾病进展恐惧量表、创伤后应激障碍平民版量表和自悯量表对其进行调查。结果 白血病患儿父母FoP总分为（39.56±8.99）分；PTSD症状总分为（34.56±12.03）分；自悯总分为（84.42±10.20）分，其中自我同情及自我批评双因素得分分别为（44.27±6.68）分和（37.87±7.53）分。Spearman分析显示，FoP与PTSD症状呈正相关，自悯与FoP、PTSD症状均呈负相关，自我批评与FoP、PTSD症状均呈正相关（均P＜0.01）。自悯在FoP和PTSD症状间起部分中介效应（18.10%），自我批评在FoP和PTSD症状间起部分中介效应（26.97%）。结论 FoP既可以直接影响PTSD症状，又可以通过自悯双因素的中介效应间接影响PTSD症状。

Objective To investigate the mediating role of self-compassion in the relationship between fear of progression (FoP) and post-traumatic stress disorder and related symptoms (PTSS) in parents of children with leukemia,so as to provide a basis for the psychological health management of these adults.Methods A total of 219 parents of children with leukemia in the Department of Paediatrics in 3 tertiary A hospitals in Guangzhou were the objects through purposive sampling method.Fear of Progression Questionnaire(parent version),the PTSD Checklist (Civilian Version) and self-compassion scale were used for investigation.Results The total score of FoP,PTSS,SCS,CS and RUS in the parents of children with leukemia were (39.56±8.99),(34.56±12.03),(84.42±10.20),(44.27±6.68),and (37.87±7.53) respectively.Spearman correlation analysis showed that FoP positively correlated with PTSS ,self-compassion negatively correlated with FoP and PTSS ,and RUS positively correlated with FoP and PTSS (all P＜0.01).The mediating analysis results showed that self-compassion played a partial mediating role in the relationship between FoP and PTSS (18.10%),and RUS played a partial mediating role in the relationship between FoP and PTSS (26.97%).Conclusions The FoP can not only directly affect PTSS,but also indirectly affect PTSS through the mediating effect of self-compassion.

R473.72

广州市科技计划项目(202201011758)；深圳市“医疗卫生三名工程”项目(SZZYSM202108013）